Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Failure to support a genetic contribution of AKT1 polymorphisms and altered AKT signaling in schizophrenia.

Journal of neurochemistry - 1 Oct 2006

Ide Masayuki, Ohnishi Tetsuo, Murayama Miyuki, Matsumoto Izuru, Yamada Kazuo, Iwayama Yoshimi, Dedova Irina, Toyota Tomoko, Asada Takashi, Takashima Akihiko, Yoshikawa Takeo

Abstract excerpt

The protein kinase v-akt murine thymoma viral oncogene homolog (AKT) gene family comprises three human homologs that phosphorylate and inactivate glycogen synthase kinase 3beta (GSK3beta). Studies have reported the genetic association of AKT1 with schizophrenia. Additionally, decreased AKT1 prote...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Glycogen Synthase Kinase 3
Share to Glycogen Synthase Kinase 3 beta

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lymphocytes

Share to Pedigree

Share to Proto-Oncogene Proteins c-akt

Share to Schizophrenia

Share to tau Proteins

Source

Identifiers

PMID: 16987250
DOI: 10.1111/j.1471-4159.2006.04033.x

Genes

AKT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16987250-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Failure to support a genetic contribution of AKT1 polymorphisms and altered AKT signaling in schizophrenia.PMID 16987250Read ↗

No association between AKT1 polymorphism and schizophrenia: a case-control study in a Korean population and a meta-analysis.Semantic proximity Read ↗

Association of AKT1 gene variants and protein expression in both schizophrenia and bipolar disorder.Semantic proximity Read ↗

Association analysis of AKT1 and schizophrenia in a UK case control sample.Semantic proximity Read ↗

Absence of significant associations between four AKT1 SNP markers and schizophrenia in the Taiwanese population.Semantic proximity Read ↗

Association of AKT1 with schizophrenia confirmed in a Japanese population.Semantic proximity Read ↗

Association of AKT1 haplotype with the risk of schizophrenia in Iranian population.Semantic proximity Read ↗

Marked reduction of AKT1 expression and deregulation of AKT1-associated pathways in peripheral blood mononuclear cells of schizophrenia patients.Semantic proximity Read ↗

AKT inhibition in the central nervous system induces signaling defects resulting in psychiatric symptomatologySemantic proximity Read ↗

AKT1 is associated with schizophrenia across multiple symptom dimensions in the Irish study of high density schizophrenia families.Semantic proximity Read ↗

No association between AKT1 gene variants and schizophrenia: a Malaysian case-control study and meta-analysis.Semantic proximity Read ↗

Association of AKT1 gene polymorphisms with risk of schizophrenia and with response to antipsychotics in the Chinese population.Semantic proximity Read ↗

A signaling pathway AKTing up in schizophrenia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.