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Article

Clonality of lobular carcinoma in situ (LCIS) and metachronous invasive breast cancer.

Breast cancer research and treatment - 1 Feb 2008

Aulmann Sebastian, Penzel Roland, Longerich Thomas, Funke Benjamin, Schirmacher Peter, Sinn Hans Peter

Abstract excerpt

Lobular carcinoma in situ (LCIS) of the breast is generally considered an indicator for a bilaterally increased risk of invasive breast cancer (IBC). However, as recent studies suggested a clonal relationship between a subset of synchronous LCIS and invasive lobular carcinomas (ILC), we aimed to examine a possible precursor role for LCIS and IBC occurring in the same breast at a later time. Out of a consecutive...

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Identifiers

PMID: 17380381
DOI: 10.1007/s10549-007-9557-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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