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Genomic profiling defines variable clonal relatedness between invasive breast cancer and primary ductal carcinoma <i>in situ</i>

2021-03-26

Abstract excerpt

Pure ductal carcinoma in situ (DCIS) is being diagnosed more frequently through breast screening programmes and is associated with an increased risk of developing invasive breast cancer. We assessed the clonal relatedness of 143 cases of pure DCIS and their subsequent events using a combination of whole exome, targeted and copy number sequencing, supplemented by single cell analysis. Unexpectedly, 18% of all invas...

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Identifiers and source

Literature Corpus work
a1c68b8c-5caa-5f22-816b-98437e1a2a3f
DOI
10.1101/2021.03.22.21253209
Open publication

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Genomic profiling defines variable clonal relatedness between invasive breast cancer and primary ductal carcinoma <i>in situ</i>DOI 10.1101/2021.03.22.21253209
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