Article
Mitochondrial DNA analysis efficiently contributes to the identification of metastatic contralateral breast cancers.
Journal of cancer research and clinical oncology - 1 Feb 2021
Girolimetti Giulia, Marchio Lorena, De Leo Antonio, Mangiarelli Miriam, Amato Laura Benedetta, Zanotti Simone, Taffurelli Mario, Santini Donatella, Gasparre Giuseppe, Ceccarelli Claudio
Abstract excerpt
PURPOSE: In daily practice, a contralateral breast cancer (CBC) is usually considered as a new independent tumor despite the indications of several studies showing that the second neoplasia may be a metastatic spread of the primary tumor. Recognition of clonal masses in the context of multiple synchronous or metachronous tumors is crucial for correct prognosis, therapeutic choice, and patient management....
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