Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mitochondrial D310 mutations in the early development of breast cancer.

British journal of cancer - 24 Apr 2012

Xu C, Tran-Thanh D, Ma C, May K, Jung J, Vecchiarelli J, Done S J

Abstract excerpt

BACKGROUND: The role of mitochondrial DNA (mtDNA) mutations in the development of breast cancer is largely unknown. In this study, we investigated the frequency and pattern of mutations in the D310 region, the most commonly mutated region in mtDNA, in a series of breast lesions. METHODS: Using capillary electrophoresis, we genotyped the D310 sequence of neoplastic epithelial cells from 23 patients with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast
Share to Breast Neoplasms
Share to Carcinoma, Ductal, Breast

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Carcinoma, Intraductal, Noninfiltrating

Share to Disease Progression

Share to DNA, Mitochondrial

Share to Mutation

Share to Repetitive Sequences, Nucleic Acid

Source

Open in PubMed Open full text

Identifiers

PMID: 22472881
DOI: 10.1038/bjc.2012.74
PMCID: PMC3341870

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mitochondrial D310 mutations in the early development of breast cancer.PMID 22472881Read ↗

Mitochondrial D310 instability in Asian Indian breast cancer patients.Semantic proximity Read ↗

Detection of mitochondrial DNA mutations in primary breast cancer and fine-needle aspirates.Semantic proximity Read ↗

Current understanding of mitochondrial DNA in breast cancer.Semantic proximity Read ↗

Mitochondrial D310 mutation as clonal marker for solid tumors.Semantic proximity Read ↗

Mitochondrial DNA alterations correlate with the pathological status and the immunological ER, PR, HER-2/neu, p53 and Ki-67 expression in breast invasive ductal carcinoma.Semantic proximity Read ↗

Paired ductal carcinoma in situ and invasive breast cancer lesions in the D-loop of the mitochondrial genome indicate a cancerization field effect.Semantic proximity Read ↗

Sequence variations of mitochondrial DNA D-loop region are highly frequent events in familial breast cancer.Semantic proximity Read ↗

Mitochondrial DNA mutations and breast tumorigenesis.Semantic proximity Read ↗

Mitochondrial DNA Mutation Analysis in Breast Cancer: Shifting From Germline Heteroplasmy Toward Homoplasmy in TumorsSemantic proximity Read ↗

Mitochondrial DNA mutations in breast cancer tissue and in matched nipple aspirate fluid.Semantic proximity Read ↗

Somatic mutations of mitochondrial genome in early stage breast cancer.Semantic proximity Read ↗

Mutations in the mitochondrial DNA D-loop region and breast cancer risk.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.