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Article

Polymorphisms in the DNA repair gene XRCC1 associated with basal cell carcinoma and squamous cell carcinoma of the skin in a Korean population.

Cancer science - 1 May 2007

Kang Sang Yoon, Lee Kwang Gil, Lee Wooseung, Shim Jeong Yun, Ji Seung Il, Chung Ki Wha, Chung Yoon Kyu, Kim Nam Keun

Abstract excerpt

DNA in most cells is regularly damaged by endogenous and exogenous mutagens. Unrepaired damage can result in apoptosis or may lead to unregulated cell growth and cancer. Inheritance of genetic variants at one or more loci results in reduced DNA repair capacity. This hospital-based case-control study examined whether polymorphisms in the DNA repair gene X-ray repair cross-complementing groups 1 (XRCC1)...

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Source

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Identifiers

PMID: 17355263
DOI: 10.1111/j.1349-7006.2007.00436.x
PMCID: PMC11158161

Genes

XRCC1

Provenance

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