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Article

Association of Environmental Arsenic Exposure, Genetic Polymorphisms of Susceptible Genes, and Skin Cancers in Taiwan.

BioMed research international - 1 Jan 2015

Hsu Ling-I, Wu Meei-Maan, Wang Yuan-Hung, Lee Cheng-Yeh, Yang Tse-Yen, Hsiao Bo-Yu, Chen Chien-Jen

Abstract excerpt

Deficiency in the capability of xenobiotic detoxification and arsenic methylation may be correlated with individual susceptibility to arsenic-related skin cancers. We hypothesized that glutathione S-transferase (GST M1, T1, and P1), reactive oxygen species (ROS) related metabolic genes (NQO1, EPHX1, and HO-1), and DNA repair genes (XRCC1, XPD, hOGG1, and ATM) together may play a role in arsenic-induced skin...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26295053
DOI: 10.1155/2015/892579
PMCID: PMC4532812

Genes

EPHX1
ATM
GSTT1
NQO1
XRCC1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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