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Article

Flux balance analysis of a genome-scale yeast model constrained by exometabolomic data allows metabolic system identification of genetically different strains.

Biotechnology progress - 1 Jan 2000

Cakir Tunahan, Efe Cagri, Dikicioglu Duygu, Hortaçsu Amable, Kirdar Betül, Oliver Stephen G

Abstract excerpt

A systems approach to biology requires a principled approach to pathway identification. In this study, the two nuclear petite yeast mutants K1Deltapet191a and K1Deltapet191ab and their parental industrial strain K1 were cultured in glucose-containing microaerobic chemostats. Exometabolomic profiles were used to infer the differences in the fermentation characteristics and respiration capacity of the strains. The...

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PMID: 17373823
DOI: 10.1021/bp060272r

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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