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Article

Identification of genome-scale metabolic network models using experimentally measured flux profiles.

PLoS computational biology - 7 Jul 2006

Herrgård Markus J, Fong Stephen S, Palsson Bernhard Ø

Abstract excerpt

Genome-scale metabolic network models can be reconstructed for well-characterized organisms using genomic annotation and literature information. However, there are many instances in which model predictions of metabolic fluxes are not entirely consistent with experimental data, indicating that the reactions in the model do not match the active reactions in the in vivo system. We introduce a method for determining...

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PMID: 16839195
DOI: 10.1371/journal.pcbi.0020072
PMCID: PMC1487183

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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