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Article

Integrative metabolic flux analysis reveals an indispensable dimension of phenotypes.

Current opinion in biotechnology - 1 Jun 2022

Law Richard C, Lakhani Aliya, O'Keeffe Samantha, Erşan Sevcan, Park Junyoung O

Abstract excerpt

Complete understanding of a biological system requires quantitation of metabolic fluxes that reflect its dynamic state. Various analytical chemistry tools, enzyme-based probes, and microscopy enable flux measurement. However, any method alone falls short of comprehensive flux quantitation. Here we show that integrating these techniques results in a systems-level quantitative map of absolute metabolic fluxes that...

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Identifiers

PMID: 35278746
DOI: 10.1016/j.copbio.2022.102701
PMCID: PMC9177643

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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