Article
Decreased fragile histidine triad expression in colorectal cancer and its association with apoptosis inhibition.
World journal of gastroenterology - 21 Feb 2007
Cao Jie, Chen Xiao-Ping, Li Wang-Lin, Xia Jie, Du Hong, Tang Wei-Biao, Wang Hui, Chen Xi-Wen, Xiao Huan-Qing, Li Yu-Yuan
Abstract excerpt
AIM: To detect the expression of fragile histidine triad (FHIT) in normal colorectal tissue, colorectal adenoma and colorectal cancer (CRC) tissue, and to analyze its relationship with the clinicopathological features of CRC, and apoptosis-associated proteins (Bcl-2, Bax, survivin) and apoptosis in colorectal cancer. METHODS: FHIT mRNA analysis was performed by nested reverse transcription-polymerase chain...
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