Article
Human dendritic cells acquire a semimature phenotype and lymph node homing potential through interaction with CD4+CD25+ regulatory T cells.
Journal of immunology (Baltimore, Md. : 1950) - 1 Apr 2007
Bayry Jagadeesh, Triebel Frédéric, Kaveri Srini V, Tough David F
Abstract excerpt
Interactions between dendritic cells (DC) and T cells are known to involve the delivery of signals in both directions. We sought to characterize the effects on human DC of contact with different subsets of activated CD4+ T cells. The results showed that interaction with CD25(high)CD4+ regulatory T cells (Tregs) caused DC to take on very different properties than contact with naive or memory phenotype T cells....
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