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Article

LPS activation is required for migratory activity and antigen presentation by tolerogenic dendritic cells.

Journal of leukocyte biology - 1 Feb 2009

Anderson Amy E, Swan David J, Sayers Bethan L, Harry Rachel A, Patterson Angela M, von Delwig Alexei, Robinson John H, Isaacs John D, Hilkens Catharien M U

Abstract excerpt

Autoimmune pathologies are caused by a breakdown in self-tolerance. Tolerogenic dendritic cells (tolDC) are a promising immunotherapeutic tool for restoring self-tolerance in an antigen-specific manner. Studies about tolDC have focused largely on generating stable maturation-resistant DC, but few have fully addressed questions about the antigen-presenting and migratory capacities of these cells, prerequisites for...

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Share to Anti-Inflammatory Agents
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 18971286
DOI: 10.1189/jlb.0608374
PMCID: PMC2700018

Genes

CCL19
CCR7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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