Article

HIV-1 Induction of Tolerogenic DCs is Mediated by Cellular Interaction with Suppressive T Cells

2021-09-01

Abstract excerpt

HIV-1 infection gives rise to a multilayered immune impairment in most infected individuals. The crosstalk between Dendritic cells and T cells plays an important part in the induction of immune responses. The chronic presence of human immunodeficiency virus (HIV)-1 during the dendritic cells (DCs) priming and activation of T cells promotes the expansion of suppressor cells in a contact dependent manner. The mechan...

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Literature Corpus work: bd8518c2-9f7b-5c08-8742-0c09ada2daff
DOI: 10.1101/2021.09.01.458353

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