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Article

Genome-wide loss of heterozygosity and copy number analysis in melanoma using high-density single-nucleotide polymorphism arrays.

Cancer research - 15 Mar 2007

Stark Mitchell, Hayward Nicholas

Abstract excerpt

Although a number of genes related to melanoma development have been identified through candidate gene screening approaches, few studies have attempted to conduct such analyses on a genome-wide scale. Here we use Illumina 317K whole-genome single-nucleotide polymorphism arrays to define a comprehensive allelotype of melanoma based on loss of heterozygosity (LOH) and copy number changes in a panel of 76 melanoma...

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Source

Identifiers

PMID: 17363583
DOI: 10.1158/0008-5472.CAN-06-4152

Genes

BRAF
CCND1
HDAC4
MITF
NRAS
PTEN
PTPRD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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