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Article

The extent of whole-genome copy number alterations predicts aggressive features in primary melanomas.

Pigment cell & melanoma research - 1 Mar 2016

Gandolfi Greta, Longo Caterina, Moscarella Elvira, Zalaudek Iris, Sancisi Valentina, Raucci Margherita, Manzotti Gloria, Gugnoni Mila, Piana Simonetta, Argenziano Giuseppe, Ciarrocchi Alessia

Abstract excerpt

Recent evidence indicates that melanoma comprises distinct types of tumors and suggests that specific morphological features may help predict its clinical behavior. Using a SNP-array approach, we quantified chromosomal copy number alterations (CNA) across the whole genome in 41 primary melanomas and found a high degree of heterogeneity in their genomic asset. Association analysis correlating the number and...

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PMID: 26575206
DOI: 10.1111/pcmr.12436

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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