Article
Copy number variation in archival melanoma biopsies versus benign melanocytic lesions.
Cancer biomarkers : section A of Disease markers - 11 Mar 2016
Mahas Ahmed, Potluri Keerti, Kent Michael N, Naik Sameep, Markey Michael
Abstract excerpt
BACKGROUND: Skin melanocytes can give rise to benign and malignant neoplasms. Discrimination of an early melanoma from an unusual/atypical benign nevus can represent a significant challenge. However, previous studies have shown that in contrast to benign nevi, melanoma demonstrates pervasive chromosomal aberrations. OBJECTIVE: This substantial difference between melanoma and benign nevi can be exploited to...
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