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Article

Identification of TFG (TRK-fused gene) as a putative metastatic melanoma tumor suppressor gene.

Genes, chromosomes & cancer - 1 May 2012

Dutton-Regester Ken, Aoude Lauren G, Nancarrow Derek J, Stark Mitchell S, O'Connor Linda, Lanagan Cathy, Pupo Gulietta M, Tembe Varsha, Carter Candace D, O'Rourke Michael, Scolyer Richard A, Mann Graham J, Schmidt Christopher W, Herington Adrian, Hayward Nicholas K

Abstract excerpt

High density SNP arrays can be used to identify DNA copy number changes in tumors such as homozygous deletions of tumor suppressor genes and focal amplifications of oncogenes. Illumina Human CNV370 Bead chip arrays were used to assess the genome for unbalanced chromosomal events occurring in 39 cell lines derived from stage III metastatic melanomas. A number of genes previously recognized to have an important...

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Source

Identifiers

PMID: 22250051
DOI: 10.1002/gcc.21932

Genes

TFG
ACTA2
CCND1
FAS
MDM2
MITF
NRAS
PTEN
PTPRD

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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