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Article

Genomic profiling of malignant melanoma using tiling-resolution arrayCGH.

Oncogene - 12 Jul 2007

Jönsson G, Dahl C, Staaf J, Sandberg T, Bendahl P-O, Ringnér M, Guldberg P, Borg A

Abstract excerpt

Malignant melanoma is an aggressive, heterogeneous disease where new biomarkers for diagnosis and clinical outcome are needed. We searched for chromosomal aberrations that characterize its pathogenesis using 47 different melanoma cell lines and tiling-resolution bacterial artificial chromosome-arrays for comparative genomic hybridization. Major melanoma genes, including BRAF, NRAS, CDKN2A, TP53, CTNNB1, CDK4 and...

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Share to Chromosome Aberrations
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Oligonucleotide Array Sequence Analysis

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Source

Identifiers

PMID: 17260012
DOI: 10.1038/sj.onc.1210252

Genes

BRAF
PTEN
NRAS
CCND1
CCNE1
CDK4
CTNNB1
MDM2
MITF
NOTCH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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