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Article

Allelic imbalances and microdeletions affecting the PTPRD gene in cutaneous squamous cell carcinomas detected using single nucleotide polymorphism microarray analysis.

Genes, chromosomes & cancer - 1 Jul 2007

Purdie Karin J, Lambert Sally R, Teh Muy-Teck, Chaplin Tracy, Molloy Gael, Raghavan Manoj, Kelsell David P, Leigh Irene M, Harwood Catherine A, Proby Charlotte M, Young Bryan D

Abstract excerpt

Cutaneous squamous cell carcinomas (SCC) are the second most commonly diagnosed cancers in fair-skinned people; yet the genetic mechanisms involved in SCC tumorigenesis remain poorly understood. We have used single nucleotide polymorphism (SNP) microarray analysis to examine genome-wide allelic imbalance in 16 primary and 2 lymph node metastatic SCC using paired non-tumour samples to counteract normal copy number...

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Share to Aged, 80 and over
Share to Carcinoma, Squamous Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosome Aberrations

Share to Loss of Heterozygosity

Share to Oligonucleotide Array Sequence Analysis

Share to Protein Tyrosine Phosphatases

Share to Receptor-Like Protein Tyrosine Phosphatases, Class 2

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Source

Open in PubMed Open full text

Identifiers

PMID: 17420988
DOI: 10.1002/gcc.20447
PMCID: PMC2426828

Genes

PTPRD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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