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Article

Infrequent mutation of the ras genes in skin tumors of xeroderma pigmentosum patients in Japan.

International journal of cancer - 1 Feb 1992

Ishizaki K, Tsujimura T, Nakai M, Nishigori C, Sato K, Katayama S, Kurimura O, Yoshikawa K, Imamura S, Ikenaga M

Abstract excerpt

By using PCR amplification and oligonucleotide mismatch hybridization, base-substitution mutations of the ras genes in 26 skin tumors of Japanese xeroderma pigmentosum (XP) patients were studied. Thin sections of tumor tissues which were fixed and embedded in paraffin blocks were used in this study. After analyzing codons 12, 13 and 61 of the H-, K- and N-ras genes by using 66 oligomer probes, we detected only...

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Identifiers

PMID: 1735606
DOI: 10.1002/ijc.2910500309

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Infrequent mutation of the ras genes in skin tumors of xeroderma pigmentosum patients in Japan.PMID 1735606Read ↗

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