Article
No evidence for the mutation of ras gene in psoriatic epidermis.
Archives of dermatological research - 1 Jan 1990
Takahashi H, Iizuka H, Katagiri M
Abstract excerpt
The ras oncogene product, ras p21, is structurally homologous to guanine nucleotide-binding proteins, which play an important role in transmembrane signaling systems. Recently, enhanced expression of ras p21 has been reported in the psoriatic hyperproliferative epidermis, in which various alterations in the transmembrane signaling systems are well established. Since ras-proto-oncogenes are known to be activated...
Topics
- Amino Acid Sequence
- Base Sequence
- Epidermis
- Female
- Gene Amplification
- Humans
- Male
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- Proto-Oncogene Proteins
- Proto-Oncogene Proteins p21(ras)