Article
Lack of evidence of Ki-ras codon 12 mutations in melanocytic lesions.
Journal of cutaneous pathology - 1 Aug 1991
Albino A P, Nanus D M, Davis M L, McNutt N S
Abstract excerpt
A number of studies have failed to detect point mutations at codon 12 in the Ki-ras gene in melanocytic neoplasms. One recent study, however, has found a high percentage of Ki-ras codon 12 point mutations. In an effort to resolve this difference, the present study examined noncultured melanocytic lesions (i.e., 5 benign nevi, 10 dysplastic nevi, and 8 primary melanomas: 4 in situ and 4 invasive) for point...
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