Article
Lack of evidence of Ki-ras codon 12 mutations in melanocytic lesions.
Journal of cutaneous pathology - 1 Aug 1991
Albino A P, Nanus D M, Davis M L, McNutt N S
Abstract excerpt
A number of studies have failed to detect point mutations at codon 12 in the Ki-ras gene in melanocytic neoplasms. One recent study, however, has found a high percentage of Ki-ras codon 12 point mutations. In an effort to resolve this difference, the present study examined noncultured melanocytic...
Topics
- Base Sequence
- Codon
- DNA, Neoplasm
- Dysplastic Nevus Syndrome
- Exons
- Genes, ras
- Humans
- Melanoma
- Molecular Sequence Data
- Mutation
- Nevus, Pigmented
- Nucleic Acid Hybridization
- Oligonucleotides
- Polymerase Chain Reaction
- Proto-Oncogene Mas
- Proto-Oncogene Proteins p21(ras)
- Skin Neoplasms