Article
Infrequent p53 mutations in arsenic-related skin lesions.
Oncology research - 1 Jan 1998
Castrén K, Ranki A, Welsh J A, Vähäkangas K H
Abstract excerpt
Oral arsenic exposure increases the risk for a variety of benign and malignant skin lesions, but the molecular mechanism of the carcinogenic effect is poorly understood. Arsenic-related squamous cell carcinomas of the skin can develop either de novo or progress from Bowen's disease lesions. Arsenic-related basal cell carcinomas develop usually in non-sun-exposed areas and are multiple. Because p53 tumor...
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