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Article

Low incidence of c-Ha-ras gene mutations in benign and malignant cutaneous lesions from transplant recipients.

International journal of cancer - 2 Dec 1993

Pélisson I, Chardonnet Y, Euvrard S, Schmitt D

Abstract excerpt

Transplant recipients successively develop benign, premalignant and malignant skin lesions on sun-exposed areas. It has been suggested that UV radiations might induce mutations in ras oncogenes and p53 tumour-suppressor gene, responsible for skin cancers. With PCR and oligoprobe hybridization, we investigated c-Ha-ras gene mutations at codons 12 and 61 in 120 cutaneous lesions from grafted patients, since they...

Topics

Animals
Base Sequence
Codon
Genes, ras
Humans
Keratoacanthoma
Molecular Sequence Data
Mutation
Precancerous Conditions
Rats
Skin Diseases
Skin Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Skin Transplantation

Warts

Source

Identifiers

PMID: 8253528
DOI: 10.1002/ijc.2910550607

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8253528-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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