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Article

Plasmodium falciparum Na+/H+ exchanger activity and quinine resistance.

Molecular and biochemical parasitology - 1 May 2007

Bennett Tyler N, Patel Jigar, Ferdig Michael T, Roepe Paul D

Abstract excerpt

Mutations in the Plasmodium falciparum pfcrt gene cause resistance to the 4-amino quinoline chloroquine (CQ) and other antimalarial drugs. Mutations and/or overexpression of a P. falciparum multidrug resistance gene homologue (pfmdr1) may further modify or tailor the degree of quinoline drug resistance. Recently [Ferdig MT, Cooper RA, Mu JB, et al. Dissecting the loci of low-level quinine resistance in malaria...

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Identifiers

PMID: 17353059
DOI: 10.1016/j.molbiopara.2007.01.018
PMCID: PMC2747254

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Source receipt: pubmed, retrieved 7 Sept 2026.

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