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Article

Dissecting the loci of low‐level quinine resistance in malaria parasites

13 Apr 2004

Abstract excerpt

Quinine (QN) remains effective against Plasmodium falciparum, but its decreasing efficacy is documented from different continents. Multiple genes are likely to contribute to the evolution of QN resistance. To locate genes contributing to QN response variation, we have searched a P. falciparum genetic cross for quantitative trait loci (QTL). Results identify additive QTL in segments of chromosomes (Chrs) 13, 7 and...

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PMID: 15130119
DOI: 10.1111/j.1365-2958.2004.04035.x

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