Article
Drug resistance-associated pfCRT mutations confer decreased Plasmodium falciparum digestive vacuolar pH.
Molecular and biochemical parasitology - 1 Jan 2004
Bennett Tyler N, Kosar Andrew D, Ursos Lyann M B, Dzekunov Sergey, Singh Sidhu Amar Bir, Fidock David A, Roepe Paul D
Abstract excerpt
Elucidating the altered physiology of various chloroquine resistant (CQR) strains of Plasmodium falciparum is essential for understanding the molecular basis of CQR. In this study, we have devised several new methods for analyzing digestive vacuolar (DV) pH for individual intraerythrocytic parasi...
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