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Article

Functional activation by central monoamines of human dopamine D(4) receptor polymorphic variants coupled to GIRK channels in Xenopus oocytes.

European journal of pharmacology - 21 May 2007

Wedemeyer Carolina, Goutman Juan D, Avale María E, Franchini Lucía F, Rubinstein Marcelo, Calvo Daniel J

Abstract excerpt

We studied the functional activation of different polymorphic variants of the human dopamine D(4) receptors by the three major central monoamines, dopamine, noradrenaline and serotonin. Dopamine D(4) receptors carrying two (D4.2), four (D4.4) or seven (D4.7) repeats within the third intracellular domain were co-expressed with G protein-regulated inwardly rectifying potassium channels (GIRK1) in frog oocytes. All...

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Identifiers

PMID: 17350612
DOI: 10.1016/j.ejphar.2007.01.055

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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