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Article

Lower rate of genomic variation identified in the trans-membrane domain of monoamine sub-class of Human G-Protein Coupled Receptors: the Human GPCR-DB Database.

BMC genomics - 4 Dec 2004

Wahlestedt Claes, Brookes Anthony J, Mottagui-Tabar Salim

Abstract excerpt

BACKGROUND: We have surveyed, compiled and annotated nucleotide variations in 338 human 7-transmembrane receptors (G-protein coupled receptors). In a sample of 32 chromosomes from a Nordic population, we attempted to determine the allele frequencies of 80 non-synonymous SNPs, and found 20 novel polymorphic markers. GPCR receptors of physiological and clinical importance were prioritized for statistical analysis....

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Share to Biogenic Monoamines
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genome, Human

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Share to Receptors, G-Protein-Coupled

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Identifiers

PMID: 15579207
DOI: 10.1186/1471-2164-5-91
PMCID: PMC538281

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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