Article
Comparative pharmacological and functional analysis of the human dopamine D4.2 and D4.10 receptor variants.
Pharmacogenetics - 1 Oct 1999
Jovanovic V, Guan H C, Van Tol H H
Abstract excerpt
The human dopamine D4 receptor is a D2-like receptor which is a target for most common neuroleptics. Previous investigations have shown that this receptor displays a large polymorphic variation in the third intracellular loop involving a variable number of direct imperfect tandem repeats (VNTR) of 16 amino acids. The shortest and longest repeat variants reported to date contain two and 10 repeat units (D4.2 and...
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