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Article

A Drosophila dopamine 2-like receptor: Molecular characterization and identification of multiple alternatively spliced variants.

Proceedings of the National Academy of Sciences of the United States of America - 29 Oct 2002

Hearn Mark G, Ren Yong, McBride Edward W, Reveillaud Isabelle, Beinborn Martin, Kopin Alan S

Abstract excerpt

Dopamine is an important neurotransmitter in the central nervous system of both Drosophila and mammals. Despite the evolutionary distance, functional parallels exist between the fly and mammalian dopaminergic systems, with both playing roles in modulating locomotor activity, sexual function, and the response to drugs of abuse. In mammals, dopamine exerts its effects through either dopamine 1-like (D1-like) or...

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PMID: 12391323
DOI: 10.1073/pnas.202498299
PMCID: PMC137921

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