Article
A case of mistaken identity? Nonductal origins of pancreatic "ductal" cancers.
Cancer cell - 1 Mar 2007
Murtaugh L Charles, Leach Steven D
Abstract excerpt
In this issue of Cancer Cell, Guerra and colleagues provide important new insights regarding the ability of specific pancreatic cell types to generate invasive pancreatic cancer. First, they demonstrate that classical pancreatic "ductal" neoplasia can be induced by activation of oncogenic Kras in nonductal exocrine cells. Second, they show that, while Kras activation in immature acinar and centroacinar cells is...
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