Article
Ductal neoplasia of the pancreas: nosologic, clinicopathologic, and biologic aspects.
Seminars in radiation oncology - 1 Oct 2005
Adsay Nazmi Volkan, Basturk Olca, Cheng Jeanette D, Andea Aleodor A
Abstract excerpt
Most pancreatic neoplasia are of ductal lineage, characterized by tubule (gland), cyst, papilla, or mucin formation and expression of mucin-related glycoproteins and oncoproteins (eg, MUC1, CA19-9, CEA, DUPAN), as well as some subsets of cytokeratin (eg, CK19). Mutations of k-ras oncogene and DPC4 are also common in ductal neoplasia and generally not seen in nonductal tumors. A variety of pancreatic neoplasia...
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