Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The cellular origins of cancer with particular reference to the gastrointestinal tract.

International journal of experimental pathology - 1 Oct 2020

Alison Malcolm R

Abstract excerpt

Stem cells or their closely related committed progenitor cells are the likely founder cells of most neoplasms. In the continually renewing and hierarchically organized epithelia of the oesophagus, stomach and intestine, homeostatic stem cells are located at the beginning of the cell flux, in the basal layer of the oesophagus, the isthmic region of gastric oxyntic glands and at the bottom of gastric pyloric-antral...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bile Duct Neoplasms
Share to Carcinoma, Pancreatic Ductal
Share to Cholangiocarcinoma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gastrointestinal Tract

Share to Metaplasia

Share to Neoplastic Stem Cells

Share to Pancreas

Share to Precancerous Conditions

Source

Open in PubMed Open full text

Identifiers

PMID: 32794627
DOI: 10.1111/iep.12364
PMCID: PMC7495846

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The cellular origins of cancer with particular reference to the gastrointestinal tract.PMID 32794627Read ↗

Stem cell relationships and the origin of gastrointestinal cancer.Semantic proximity Read ↗

The gastrointestinal stem cellSemantic proximity Read ↗

[Etiology and carcinogenesis of pancreatic ductal adenocarcinoma].Semantic proximity Read ↗

Paneth cells as the origin of intestinal cancer in the context of inflammationSemantic proximity Read ↗

Single-cell transcriptomics reveals a conserved metaplasia program in pancreatic injurySemantic proximity Read ↗

Liver cancer: the role of stem cellsSemantic proximity Read ↗

The Origins of Gastric Cancer From Gastric Stem Cells: Lessons From Mouse ModelsSemantic proximity Read ↗

The role of TGF-beta and Wnt signaling in gastrointestinal stem cells and cancer.Semantic proximity Read ↗

Mutational spectrum of Barrett's stem cells suggests paths to initiation of a precancerous lesion.Semantic proximity Read ↗

The cancer cells-of-origin in the gastrointestinal tract: progenitors revisited.Semantic proximity Read ↗

Gastrointestinal stem cells.Semantic proximity Read ↗

The hepatic, biliary, and pancreatic network of stem/progenitor cell niches in humans: A new reference frame for disease and regenerationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.