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Article

Genetic polymorphisms of the urea transporter gene are associated with antihypertensive response to nifedipine GITS.

Methods and findings in experimental and clinical pharmacology - 1 Jan 2000

Hong X, Xing H, Yu Y, Wen Y, Zhang Y, Zhang S, Tang G, Xu X

Abstract excerpt

Nifedipine GITS has diuretic and natriuretic properties, which may enhance its antihypertensive efficacy. We assessed contributions of polymorphisms in the urea transporter-A gene (SLC14A2) to interindividual variations in blood pressure (BP) response to nifedipine treatment. 405 subjects from a single Chinese county received a single oral dose of 30 mg nifedipine GITS (gastrointestinal therapeutic system) daily...

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Source

Identifiers

PMID: 17344938
DOI: 10.1358/mf.2007.29.1.1063490

Genes

DBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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