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Article

ABCG2 rs2231142 variant in hyperuricemia is modified by SLC2A9 and SLC22A12 polymorphisms and cardiovascular risk factors in an elderly community-dwelling population.

BMC medical genetics - 17 Mar 2020

Liu Jia, Yang Wei, Li Yun, Wei Zhanyun, Dan Xiaojuan

Abstract excerpt

BACKGROUND: The ABCG2 rs2231142 single nucleotide polymorphism (SNP) is one of the most significant genetic variants associated with hyperuricemia (HUA) in Asian populations. However, the risk of ABCG2 rs2231142 variants for HUA could interact with other important HUA risk variants and cardiovascular factors. This study investigated the effects of the combined association among ABCG2 rs2231142 and multiple HUA...

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Share to ATP Binding Cassette Transporter, Subfamily G, Member 2
Share to Genes, Modifier
Share to Glucose Transport Proteins, Facilitative
Share to Hyperuricemia
Share to Independent Living
Share to Organic Anion Transporters
Share to Organic Cation Transport Proteins
Share to Uric Acid

Source

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Identifiers

PMID: 32183743
DOI: 10.1186/s12881-020-0987-4
PMCID: PMC7077001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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