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Article

The impact of an URAT1 polymorphism on the losartan treatment of hypertension and hyperuricemia.

Journal of clinical laboratory analysis - 1 Oct 2021

Wu Liting, Fan Yingchao, Wang Yuan, Li Zhumeng, Mao Delong, Zhuang Wenfang

Abstract excerpt

BACKGROUND: This study was designed to evaluate the impact of polymorphisms in the urate transporter 1 (URAT1) gene on the uricosuric action of losartan therapy in hypertensive patients suffering from hyperuricemia. METHODS: A MassARRAY approach was used to detect single nucleotide polymorphism (SNP) loci in the URAT1 and CYP2C9 genes (16 and 2 loci, respectively) in 111 patients with hypertension and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34498315
DOI: 10.1002/jcla.23949
PMCID: PMC8529133

Genes

CYP2C9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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