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Article

Molecular correlates with MGMT promoter methylation and silencing support CpG island methylator phenotype-low (CIMP-low) in colorectal cancer.

Gut - 1 Nov 2007

Ogino Shuji, Kawasaki Takako, Kirkner Gregory J, Suemoto Yuko, Meyerhardt Jeffrey A, Fuchs Charles S

Abstract excerpt

BACKGROUND: The CpG island methylator phenotype (CIMP or CIMP-high) with widespread promoter methylation is a distinct epigenetic phenotype in colorectal cancer. In contrast, a phenotype with less widespread promoter methylation (CIMP-low) has not been well characterised. O-6-methylguanine-DNA me...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17339237
DOI: 10.1136/gut.2007.119750
PMCID: PMC2095664

Genes

MGMT
KRAS
CRABP1
IGF2
MLH1
NEUROG1
RUNX3
SOCS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17339237-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Molecular correlates with MGMT promoter methylation and silencing support CpG island methylator phenotype-low (CIMP-low) in colorectal cancer.PMID 17339237Read ↗

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