Article
Developmental regulation of DUOX1 expression and function in human fetal lung epithelial cells.
American journal of physiology. Lung cellular and molecular physiology - 1 Jun 2007
Fischer Horst, Gonzales Linda K, Kolla Venkatadri, Schwarzer Christian, Miot Françoise, Illek Beate, Ballard Philip L
Abstract excerpt
The purpose of this study was to determine the expression and cellular functions of the epithelial NADPH oxidase DUOX1 during alveolar type II cell development. When human fetal lung cells (gestational age 11-22 wk) were cultured to confluency on permeable filters, exposure of cells to a hormone mixture (dexamethasone, 8-Br-cAMP, and IBMX, together referred to as DCI) resulted in differentiation of cells into a...
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