Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Thyroid Transcription Factor in Differentiating Type II Cells

7 Sept 2006

Abstract excerpt

Thyroid transcription factor-1 (TTF-1, product of the Nkx2.1 gene) is essential for branching morphogenesis of the lung and enhances expression of surfactant proteins by alveolar type II cells. We investigated expression of two TTF-1 mRNA transcripts, generated by alternative start sites and coding for 42- and 46-kD protein isoforms in the mouse, during hormone-induced differentiation of human fetal lung type II...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetics and Neurodevelopmental Disorders
Share to RNA modifications and cancer
Share to Thyroid Disorders and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16960125
DOI: 10.1165/rcmb.2006-0207oc

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Thyroid Transcription Factor in Differentiating Type II CellsPMID 16960125Read ↗

Gene Structure and Expression of Human Thyroid Transcription Factor-1 in Respiratory Epithelial CellsSemantic proximity Read ↗

Thyroid transcription factor-1 (TTF-1/Nkx2.1/TITF1) gene regulation in the lungSemantic proximity Read ↗

Regulated gene expression in cultured type II cells of adult human lung.Semantic proximity Read ↗

TRβ activation confers AT2-to-AT1 cell differentiation and anti-fibrosis during lung repair via KLF2 and CEBPASemantic proximity Read ↗

Whole-Genome Analysis of Temporal Gene Expression during Early Transdifferentiation of Human Lung Alveolar Epithelial Type 2 Cells In VitroSemantic proximity Read ↗

Thyroid transcription factors in development, differentiation and disease.Semantic proximity Read ↗

TGT3, thyroid transcription factor I, and Sp1 elements regulate transcriptional activity of the 1.3-kilobase pair promoter of T1alpha, a lung alveolar type I cell gene.Semantic proximity Read ↗

Respiratory insufficiency in a newborn with congenital hypothyroidism due to a new mutation of TTF-1/NKX2.1 gene.Semantic proximity Read ↗

UGRP1, a Uteroglobin/Clara Cell Secretory Protein-Related Protein, Is a Novel Lung-Enriched Downstream Target Gene for the T/EBP/NKX2.1 Homeodomain Transcription FactorSemantic proximity Read ↗

Transcription factors in mouse lung development and function.Semantic proximity Read ↗

Thyroid transcription factor-1 (TTF-1) gene: identification of ZBP-89, Sp1, and TTF-1 sites in the promoter and regulation by TNF-α in lung epithelial cells.Semantic proximity Read ↗

Lethal respiratory failure and mild primary hypothyroidism in a term girl with a de novo heterozygous mutation in the TITF1/NKX2.1 gene.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.