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Article

Roles of DUOX-Mediated Hydrogen Peroxide in Metabolism, Host Defense, and Signaling

7 Sept 2013

Abstract excerpt

SIGNIFICANCE: Among the NADPH oxidases, the dual oxidases, DUOX1 and DUOX2, constitute a distinct subfamily initially called thyroid oxidases, based on their high level of expression in thyroid tissue. Genetic alterations causing inherited hypothyroidism clearly demonstrate their physiological implication in thyroid hormonogenesis. However, a growing list of biological functions triggered by DUOX-dependent...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 24161126
DOI: 10.1089/ars.2013.5602

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Roles of DUOX-Mediated Hydrogen Peroxide in Metabolism, Host Defense, and SignalingPMID 24161126Read ↗

Conformation of the N-Terminal Ectodomain Elicits Different Effects on DUOX Function: A Potential Impact on Congenital Hypothyroidism Caused by a H2O2 Production Defect.Semantic proximity Read ↗

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