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Article

Heterodimerization controls localization of Duox-DuoxA NADPH oxidases in airway cells

1 Apr 2009

Abstract excerpt

Duox NADPH oxidases generate hydrogen peroxide at the air-liquid interface of the respiratory tract and at apical membranes of thyroid follicular cells. Inactivating mutations of Duox2 have been linked to congenital hypothyroidism, and epigenetic silencing of Duox is frequently observed in lung cancer. To study Duox regulation by maturation factors in detail, its association with these factors, differential use...

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Identifiers

PMID: 19339556
DOI: 10.1242/jcs.044123

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Heterodimerization controls localization of Duox-DuoxA NADPH oxidases in airway cellsPMID 19339556Read ↗

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