Article
Molecular determinants of HIV-1 intersubtype recombination potential.
Virology - 5 Jul 2007
Chin Mario P S, Chen Jianbo, Nikolaitchik Olga A, Hu Wei-Shau
Abstract excerpt
Sequence differences in the dimerization initiation signal (DIS) affect the rate of recombination between subtype B and subtype C HIV-1. To test the hypothesis that DIS sequences can be used to predict intersubtype recombination potentials, we measured the recombination rate between CRF01_A/E (AE) and B, which contain mismatches in the DIS, and between AE and C, which have an identical DIS. Compared with the...
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