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Article

Constraints from protein structure and intra-molecular coevolution influence the fitness of HIV-1 recombinants.

Virology - 1 Apr 2014

Woo Jeongmin, Robertson David L, Lovell Simon C

Abstract excerpt

A major challenge for developing effective treatments for HIV-1 is the viruses' ability to generate new variants. Inter-strain recombination is a major contributor to this high evolutionary rate, since at least 20% of viruses are observed to be recombinant. However, the patterns of recombination...

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Share to Evolution, Molecular
Share to Genome, Viral
Share to HIV-1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HIV Infections

Share to Human Immunodeficiency Virus Proteins

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Share to Recombination, Genetic

Share to Selection, Genetic

Source

Identifiers

PMID: 24725929
DOI: 10.1016/j.virol.2014.01.029

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24725929-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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