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Article

Sequence analysis of the dimerization initiation site of concordant and discordant viral variants superinfecting HIV type 1 patients.

AIDS research and human retroviruses - 1 Nov 2011

Mayr Luzia, Powell Rebecca, Kinge Thompson, Nyambi Phillipe N

Abstract excerpt

For HIV recombination to occur, the RNAs from two infecting strains within a cell must dimerize at the dimerization initiation site (DIS). We examined the sequence identity at the DIS (697-731 bp, Hxb2 numbering engine) in patients superinfected with concordant HIV-1 strains and compared them to those with discordant strains. Viral RNA in sequential plasma from four subjects superinfected with subtype-discordant...

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Identifiers

PMID: 21453132
DOI: 10.1089/AID.2011.0010
PMCID: PMC3206772

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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