Article
In vitro dynamics of HIV-1 BF intersubtype recombinants genomic regions involved in the regulation of gene expression.
Virology journal - 16 Jul 2009
Carobene Mauricio G, Rodríguez Rodrígues Christian, De Candia Cristian A, Turk Gabriela, Salomón Horacio
Abstract excerpt
HIV-1 intersubtype recombination is a very common phenomenon that has been shown to frequently affect different viral genomic regions. Vpr and Tat are viral proteins known to interact with viral promoter (LTR) during the replication cycle. This interaction is mainly involved in the regulation of viral gene expression, so, any structural changes in the LTR and/or these regulatory proteins may have an important...
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