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Article

Functional bottlenecks for generation of HIV-1 intersubtype Env recombinants.

Retrovirology - 23 May 2015

Bagaya Bernard S, Vega José F, Tian Meijuan, Nickel Gabrielle C, Li Yuejin, Krebs Kendall C, Arts Eric J, Gao Yong

Abstract excerpt

BACKGROUND: Intersubtype recombination is a powerful driving force for HIV evolution, impacting both HIV-1 diversity within an infected individual and within the global epidemic. This study examines if viral protein function/fitness is the major constraint shaping selection of recombination hotspots in replication-competent HIV-1 progeny. A better understanding of the interplay between viral protein...

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Share to HIV Envelope Protein gp120

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25997955
DOI: 10.1186/s12977-015-0170-8
PMCID: PMC4445978

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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