Article
Proteasomal degradation of the KLF5 transcription factor through a ubiquitin-independent pathway.
FEBS letters - 20 Mar 2007
Chen Ceshi, Zhou Zhongmei, Guo Peng, Dong Jin-Tang
Abstract excerpt
KLF5 is a Kruppel-like zinc finger transcription factor modulating cell proliferation, differentiation, cell cycle, apoptosis, and angiogenesis. The KLF5 protein undergoes multiple posttranslational modifications including phosphorylation, acetylation and ubiquitination. We have demonstrated that...
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