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Article

The Ufm1-activating enzyme Uba5 is indispensable for erythroid differentiation in mice

8 Feb 2011

Abstract excerpt

Post-translational protein modifications are systems designed to expand restricted genomic information through functional conversion of target molecules. Ubiquitin-like post-translational modifiers regulate numerous cellular events through their covalent linkages to target protein(s) by an enzymatic cascade analogous to ubiquitylation consisting of E1 (activating), E2 (conjugating) and E3 (ligating) enzymes. In...

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PMID: 21304510
DOI: 10.1038/ncomms1182

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The Ufm1-activating enzyme Uba5 is indispensable for erythroid differentiation in micePMID 21304510Read ↗

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